An artificial pancreas is a technology that can improve basal insulin delivery,
An artificial pancreas, or closed insulin delivery system, monitors blood sugar levels, calculates the amount of insulin needed, and delivers insulin directly from a pump.
A functioning pancreas, or closed system, allows your insulin pump to “tell” you on your continuous blood glucose monitor (CGM). Depending on your blood sugar level and direction, this device will automatically adjust the insulin level delivered by your pump.
The technology can change people’s lives, make living with diabetes easier, and help people maintain stable blood sugar levels.
Where It All Started
In 1977 we bought the UK’s first artificial pancreas to help Professor Sir George Alberti manage the blood sugar levels of people with type 1 diabetes during surgery and childbirth.
It was the size of a binder. Since then, we have continued to support research to improve this technology, and have seen exciting progress.
- Creating a pancreas for type 1 diabetes
- Professor Roman Hovorka helped develop and test the pancreas
- Professor Hovorka has led the world’s first pancreas research
Professor Roman Hovorka at the University of Cambridge worked on the first pancreatic model. With our funding, he tested it in a first global trial, where 24 people with type 1 diabetes used the device at home for a month.
We got the results in 2014. People using the system stayed 13.5% longer with their blood sugar levels at a healthy level, compared to those using standard insulin therapy. They also have low overnight blood sugar without hypos. Mark Wareham, from Cambridge, has type 1 diabetes since the age of 27. He joined the trial in 2013.
Benefits for Pregnant Women With Type 1 Diabetes
A few years later, we hosted another world exhibition. Professor Helen Murphy has studied how the pancreas can help women with type 1 diabetes during pregnancy, when disease control becomes more difficult.
In 2016, the trial of Professor Murphy showed that the device was safe and improved blood sugar control in 16 pregnant women who participated and, most importantly, led to the birth of children and babies.
Laura Carver is one of the women who participated when she was pregnant with Sonny (pictured). Plan
And People With Type 2 Diabetes During Hospital Stay
We gave Professor Hovorka money to conduct one of the first tests of the pancreas in patients with diabetes 2. The results, in 2018, showed that the device can change the care of some people with diabetes from type 2 receiving in hospital time. The trial took place in two hospitals in the UK and Switzerland and involved 136 people with type 2 diabetes who needed insulin to manage their condition.
Those who used pancreatic surgery stayed almost 25% longer with blood sugar levels in the target range, compared to those who used insulin injections, without 카지노사이트 주소 significant risk of hypoglycemia. The future
Researchers are working to develop and test a functional system that uses both insulin and another hormone, called glucagon. Glucagon raises blood sugar and can be given to help people avoid hypos and control blood sugar even more.
In early clinical trials, a dual hormone system has been shown to improve endurance compared to an artificial pancreas that delivers insulin alone.
Next, scientists hope to develop a fully functional pancreas, which will eliminate the need for diabetics to manually count and add carbohydrates to get insulin during meals. It will dramatically change your day-to-day diabetes management and mean you don’t have to worry about short-term or long-term blood sugar control.
With more research, we’ll be closer to making the pancreas an everyday technology.